Clinical note
Case 1
Imp: Meningitis, viral/bacterial
Clinical insufficiency: Pt refused lumbar puncture (LP) for infection diagnostic
Treatment:
1. IV Acyclovir 400mg TDS
2. IV Cefoperazone 2g BD
Pharmaceutical Care:
1. Tx w Acyclovir was initiated till day3; restarted again on Day5 (equivalently missed 4 doses). In any case, if resistant occur when patient’s vitals and health deteriorate, what will be the next Tx in line? What with the limited evidence to show that viral meningitis has a straightforward medication to treat, let it be Herpes Virus Simplex (HVS) infection to be treated now. This is clinically rational as patient had refused LP for further diagnosis.
- IF acyclovir 400mg TDS was unable to improve patient’s clinical signs, addition to (investigational) FBP and C&S negative results, FOSCARVIR (foscarnet) 40 mg/kg q12h (renal insufficiency pt) Equivalent to 40 mg/kg q8h.
- bedrest, hydration, monitor electrolytes
- Cefoperazone 2g bd continued for any prevention of risk for bacterial infection
- Both anti-infectives to be used for a period of 10 days
Reminds me of House. Finished 3rd season and everyone has left or been fired. Can’t wait for season 4.
Unfortunately, i m not smart enuf to know all the medical stuff buhuhu but interesting to know some facts from his clinic works.
dGodfather, on 8-21-2007 @ 5:59 pm |